2002 Establishment of the Nation’s Memory Institute;
2003 Election of the Chairman and Vice-chairman of the Board of Directors of the Nation’s Memory Institute, as well as the election of all other members of the Board of Directors and Supervisory Board;
Beginning of the Institute’s activities and cooperation with institutions in Slovakia and abroad;
Beginning of delimitation of documents of the security files to ÚPN;
2004 Beginning of disclosing the electronic copies of protocols of dossiers led by the State Security on people or subjects in Slovakia on the ÚPN website;
The pilot issue of the quarterly journal Pamäť národa (Nation’s Memory);
2005 Establishment of the production unit Oral History focused on documenting the crimes of Communism;
Cooperation in building the monument Brána Slobody (Gate of Freedom) on the former Iron Curtain at the confluence of the Danube and Morava rivers, dedicated to commemorating four hundred men, women and children murdered when trying to escape to freedom in the years 1948–1989;
Signing the Agreement on Cooperation with the Historical Archives of the Hungarian State Security (22nd November 2005);
2006 Act no. 219/2006 Coll. on Anti-Communist Resistance was passed and came into force;
Granting the status of anti-Communist resistance participant to individuals who actively expressed their resistance against the Communist regime in the years 1944–1989;
Signing the Agreement on Cooperation with the Institute of National Remembrance in Poland (1st June 2006);
2007 Filing the first four motions with the General Prosecution of the Slovak Republic regarding the criminal proceedings pursuant to the Nation’s Memory Act;
Organizing the international conference NKVD/KGB Activities and its Cooperation with other Secret Services in Central and Eastern Europe 1945-1989 (14th–16th November 2007);
2008 Signing the Foundation Paper of the European Network of Official Authorities in Charge of the Secret-Police Files with partner institutions from Germany, Czech Republic, Poland, Hungary, Romania and Bulgaria (16th December 2008);
Signing the Agreement on Cooperation with the Institute for the Study of Totalitarian Regimes and Security Services Archive, Czech Republic (6th November 2008);
2009 Signing the Agreement on Cooperation with the European Network Remembrance and Solidarity Foundation;
2010 Joining the initiative for founding the Platform of European Memory and Conscience;
Granting the status of anti-Communist resistance veteran to citizens, who were in years 1944-1989 imprisoned for their active fight against the Communist power;2010 Organizing the pilot year of the film festival named Festival of Freedom;
2011 The second phase of delimitation of personal files of the State Security members;
Agreement on Cooperation with the National Council for the Study of the Securitate Archives, Romania (14th July 2011);
2012 Presidency of the European Network of Official Authorities in Charge of the Secret Police Files;
2013 Cooperation in building the monument to commemorate the Iron Curtain victims in Bratislava – Devínska Nová Ves, who lost their lives when trying to escape to Austria through the Morava river;
2014 Organizing the international scientific conference 1989 - Year of Change on the occasion of the 25th anniversary of the fall of the Communist regime in Czechoslovakia;
2015 Upgrade of the ÚPN website with a new visual and creation of ÚPN profiles on the Facebook social network and YouTube channels;
2016 Cooperation in building the memorial tablet dedicated to commemorating one of the Iron Curtain victims, an 18-year-old Hartmut Tautz from the former GDR;
Organizing the II. block of the conference entitled Justice and Criminal-Law Dealing with the Crimes of Totalitarian Regimes at the occasion of the Europe-wide Day of Remembrance for the victims of all totalitarian and authoritarian regimes within the Slovak Presidency of the Council of the European Union;
2017 Amendment of the Nation’s Memory Act, which established the Board of Directors as the statutory body of the Nation’s Memory Institute;
Issuance of the Ruling of the Constitutional Court of the Slovak Republic, pursuant to which the ÚPN shall not bear responsibility for the data veracity stated in the State Security documents;
2018 Organizing the international scientific conference dedicated to the rise of the Communist regime in former Czechoslovakia in Bratislava;
Launching the websites pursuing the milestones in the history of the Communist regime in Slovakia – the takeover of power in February 1948 and the Warsaw Pact invasion of Czechoslovakia in August 1968;
2019 Presidency of the European Network of Official Authorities in Charge of the Secret Police Files;
2020 Amendment of Act no. 274/2007 Coll. on Pension Supplements for Political Prisoners granting the anti-Communist resistance veterans increased monthly supplement and a one-off pension supplement;
Changes in the organizational structure of the ÚPN – reorganization into 3 departments;
Agreement on Cooperation with the Security Service of Ukraine (20th February 2020);
2021 allocation of real estate properties to the administration of the ÚPN as its seat.